FORMULASI DAN UJI STABILITAS SEDIAAN LOSIO PERBANDINGAN SETIL ALKOHOL DAN KARAGENAN EKSTRAK BUNGA KAMBOJA PUTIH (Plumeria acuminata) SEBAGAI ANTIOKSIDAN
نویسندگان
چکیده
Antioksidan merupakan salah satu senyawa yang dapat menangkal radikal bebas. Salah tanaman sebagai sumber antioksidan alami yaitu Bunga Kamboja Putih (Plumeria acuminata). Tujuan penelitian ini untuk mengetahui formulasi sediaan losio perbandingan setil alkohol dan karagenan ekstrak bunga kamboja putih memenuhi karakteristik stabilitas baik dengan metode cycling test (disimpan pada suhu 40℃ 4℃ selama 6 siklus). Parameter diamati organoleptis, homogenitas, pH, daya sebar viskositas. Ekstraksi menggunakan maserasi pelarut etanol 70% 4 hari diperoleh rendemen sebesar 10,6%. Analisis fitokimia meliputi alkaloid, flavonoid, saponin tannin. Ekstrak memiliki aktivitas nilai IC50 38,50 ppm sedangkan formula VII 59,19 VIII 44,8 ppm. Uji I – menghasilkan pengujian stabil parameter homogenitas pH ke-1 sampai 12. Sedangkan terjadi ketidakstabilan I, II, III ke-11 12 penambahan alkohol. viskositas viskometer rheosys memperoleh hasil 3,51 Pa.s 0,69 alkohol.Kata kunci : Antioksidan, Putih, Stabilitas, Losio, DPPH.
منابع مشابه
Yang Dan
Yang Dan Howard Hughes Medical Institute and the University of California, Berkeley Yang Dan is a Paul Licht Distinguished Professor in Biology and an Investigator of the Howard Hughes Medical Institute at the University of California, Berkeley. She grew up in Beijing and studied physics as an undergraduate student at Peking University. She conducted her PhD research in the lab of Mu-ming Poo a...
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ژورنال
عنوان ژورنال: Jurnal Ilmu Kedokteran dan Kesehatan : Journal of Medical and Health Sciences
سال: 2023
ISSN: ['2355-7583', '2549-4864']
DOI: https://doi.org/10.33024/jikk.v10i2.8728